On the morning of August 4, Shuangwei Biology held a knowledge lecture on new PRP treatment technologies. This activity was initiated by Pan Zong's assistant organization, explained by Chief Engineer Hu, and all departments of the company actively participated.

At present, foreign PRP technology is relatively mature than domestic, foreign enterprises such as REV-MED lnc, REGEN LAB SA have carried out the preparation of PRP and applied to the market, the domestic industry is also actively carrying out research. Sunway Bio has been committed to the development and production of blood transfusion equipment for nearly 20 years. PRP technology involves the preparation of blood components. At the same time, due to its wide application range and increasingly clear treatment methods, we have begun to focus on the development and application of PRP preparation equipment.

PRP Introduction

The full name of PRP is platelet-rich plasma, Chinese nameForPlatelet-rich plasma, a platelet concentrate extracted from autologous blood by centrifugation, contains high concentrations of platelets, white blood cells and fibrin,Platelet activation can release a variety of growth factors--PDGF or TGF-β orVEGFThese growth factorscan regulate cell growth and differentiation,It plays an important role in immune regulation, neuroprotection, tissue repair and bone stability.

Preparation of PRP

PRP is recommended to be used immediately after production, so aseptic preparation is extremely critical. At present, the preparation suit on the market are different, and the preparation methods are widely different. The main principles are as follows:

Venous blood collection is centrifuged in a centrifuge tube containing anticoagulant, red blood cells 3-5mm below the interface are extracted and discarded, then the upper plasma is extracted, anticoagulant is added again for secondary centrifugation, PPP is obtained in the upper layer after centrifugation, PRP is obtained in the lower layer, and then placed in the affected part or injected for treatment.

Application areas of PRP

Sports injury areas:

1、acute and chronic tendon and ligament injuries

2、Tendinopathy such as tennis elbow, plantar aponeurosis

Wound repair field

Acute and chronic soft tissue difficult to heal wounds (such as sinus, sores, diabetic foot, etc.) to accelerate healing, reduce scars, reduce pain.

medical beauty field

1, acne scars

2. Androgenetic alopecia

3. Adjuvant treatment of fat filling

Bone Repair and Joint Surgery:

1. Fracture, bone defect, osteoarthritis

2, articular cartilage injury, etc.

In orthopedics, the concept of "PRP" was born in the 1970 s. In 2011, the American Orthopaedic Association (The American Academy of Orthopaedic Surgeons) proposed PRP as an unproven but promising treatment. In 2018, the Orthopaedic Association of the Chinese Medical Association listed growth factors and platelet-rich plasma as one of the treatment methods of osteoarthritis (osteoarthritis,OA) for the first time in the 2018 edition of the guidelines for the diagnosis and treatment of osteoarthritis. The application of PRP is becoming more and more standardized, and it has also made great progress in other medical beauty and wound repair fields.

Contraindications

PRP is derived from autologous whole blood and is applied to the body only after a short period of in vitro centrifugation. There is no risk of immune rejection or disease transmission, and the safety is good, but a few contraindications should be paid attention:

1. Acute infectious arthritis;

2. Patients with obvious swelling and effusion of joints caused by other diseases cannot be ruled out;

3, coagulation abnormalities, such as platelet dysfunction syndrome, severe thrombocytopenia;

4. Septicemia

The economic research of PRP therapy shows that the therapy is lower cost and more effective than other conceivable therapies, the future of PRP therapy is promising, and the preparation technology of PRP needs to be further optimized.

Contributor: Wang Yiwei, Shi Jun

typesetting: shi jun