What are chronic wounds?  
Complex wounds that fail to heal within a normal time frame. Examples include diabetic foot ulcers, pressure injuries, osteomyelitis, open fractures, surgical incision infections, etc. They also refer to complex wounds or wounds that respond poorly to traditional treatments.  
The clinical treatment of chronic and refractory wounds is a complex process, which can involve two advanced therapeutic techniques: negative pressure drainage technology and PRP technology.

Negative Pressure Wound Therapy (NPWT) is an advanced medical technology that promotes wound healing through negative pressure suction. Using a negative pressure suction device, the wound is covered or filled with special dressings (such as polyvinyl alcohol hydrated alginate foam) to form a closed space. The negative pressure continuously suctions exudate, necrotic tissue and inflammatory mediators, while stimulating local blood circulation, promoting the growth of granulation tissue and accelerating wound healing.
What conditions are required to carry out negative pressure wound therapy? They include a negative pressure source, a membrane, and transmission media (such as porous dressings, drainage tubes, collection devices, etc.).

PRP technology, namely Platelet-Rich Plasma technology, is an innovative medical method that utilizes the patient's own blood components to promote tissue repair and regeneration.

Through centrifugation technology, high-concentration platelets, white blood cells, fibrin and various growth factors (such as platelet-derived growth factor PDGF, vascular endothelial growth factor VEGF, etc.) are extracted from the patient's autologous whole blood to prepare platelet concentrate. These growth factors can activate cell proliferation, promote angiogenesis, accelerate tissue repair, and exert anti-inflammatory effects.
The implementation of PRP technology must be centered on "aseptic operation, precise preparation, and safe application", and combined with hardware equipment, personnel capabilities, and standardized management to fully exert its role in promoting tissue repair.

The combination of Negative Pressure Wound Therapy (NPWT) and Platelet-Rich Plasma (PRP) technology has become an important combined treatment regimen in the management of chronic refractory wounds in recent years. These two technologies can accelerate wound healing through complementary mechanisms.
NPWT creates a local environment that is "clean, moist and rich in blood supply" for PRP, improving the utilization efficiency of growth factors in PRP; PRP, on the basis of NPWT, further enhances cell activity and tissue regeneration ability, and shortens the wound healing cycle.

Compared with the use of a single technology, the core advantages of the combined application of the two include:

Accelerating healing speed: It is especially suitable for chronic wounds that are unresponsive to conventional treatments. Studies have shown that it can shorten the healing time by 30%-50%.

Reducing the risk of infection: The drainage effect of NPWT reduces bacterial colonization, and the growth factors in PRP also have certain anti-inflammatory and immunomodulatory effects.

Lowering the amputation rate: For high-risk wounds such as diabetic foot ulcers, the combined use can increase the probability of limb salvage and reduce severe complications.

High safety: PRP is derived from the patient's own body, so allergic and rejection reactions are rare; when NPWT is operated in a standardized manner, the incidence of complications (such as bleeding and pain) is low.

In conclusion, the combination of NPWT and PRP provides an efficient treatment regimen for chronic refractory wounds through the dual mechanism of "drainage and purification + growth factor enhancement". However, it is necessary to strictly grasp the indications and standardize the operation procedures to maximize the therapeutic effect and reduce complications.

Nanjing Shuangwei Biotechnology Co., Ltd. (hereinafter referred to as Shuangwei Biotechnology) is an innovative medical device enterprise, founded in 2001, with the two main businesses of Safe Blood Transfusion and Wound Therapy as the core, supported by the three major platforms of Sterilization Service Platform, Medical Device Agent Platform, New Material R&D And Manufacturing Platform, focusing on the research and development, production, sales and service of new disposable medical consumables.

Product Features of Shuangwei Biotechnology Portable Negative Pressure Wound Therapy Device：
1.Convenient and Portable Use  
Patients do not need to rely on central negative pressure equipment in hospitals. The device can be carried around, expanding the range of activities and improving the quality of life. Clinical trials have shown that this product is particularly suitable for home use by patients with limited access to transportation.
2.Multiple Working Modes  
During clinical treatment, different wounds have varying requirements for pressure mode selection. In response to this characteristic, we have set up different working modes for clinical choice, which is conducive to wound healing.
3.Comprehensive Alarm Functions  
To ensure the safety and effectiveness of the device during use, R&D engineers have designed a more secure voice alarm system by starting from real-world usage scenarios and repeatedly simulating possible abnormal conditions. It features four types of voice alarm functions, facilitating safe operation for users in various clinical situations.
4.Excellent Performance  
Equipped with a built-in 2000mAh lithium battery, the device features low power consumption, enabling approximately 10-12 hours of operation when fully charged. It can generate a maximum negative pressure of 300mmHg and has a maximum fluid storage capacity of 80ml, making it suitable for draining various acute wounds, chronic non-healing wounds, and surgical wounds with heavy exudation.

The Shuangwei Biotechnology PRP kit has the following advantages:
1.High degree of automation: The preparation and extraction process is fully automated. It is composed of a disposable platelet-rich plasma preparation kit and a medical centrifuge, achieving "one-time centrifugation, one-stop sealing, and one-click preparation", reducing manual operation errors and improving the preparation efficiency and accuracy.

2.Completely closed and pollution-free: The separation and extraction process is completely closed, effectively avoiding external pollution, reducing the risk of infection, and ensuring the quality, safety and reliability of the prepared PRP.

3.Convenient operation: The PRP with the required concentration can be obtained only through one-time centrifugation. The whole preparation process only takes 15 minutes, which greatly shortens the preparation time and improves the clinical work efficiency.

4.Precise and adjustable concentration: Through mode selection, the concentration can be precisely adjusted from 2 to 8 times. It can provide personalized PRP concentrations according to the conditions and treatment needs of different patients to achieve the best treatment effect.

5.Adjustable components: Consumables can be optionally configured to prepare leukocyte PRP or complex leukocyte PRP, realizing the adjustability of PRP components and further meeting the needs of different clinical application scenarios.