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Why is the therapeutic effect of some PRP treatments not optimal?
27 Aug,2025

In the medical field, Platelet-Rich Plasma (PRP) therapy has attracted considerable attention in recent years. It is like a magical key, bringing new hope for the treatment of many diseases, especially in the areas of diabetic foot, orthopedic conditions, and wound repair. However, just as the quality of milk on the market varies, not all treatments labeled as PRP can achieve the expected results, and the key factor behind this is quality control.
Simply put, PRP (Platelet-Rich Plasma) is a platelet concentrate extracted from autologous blood through centrifugation. Platelets are rich in a variety of growth factors, and these growth factors act like "commanders" for the repair of body tissues—they can promote cell proliferation and differentiation, accelerate matrix synthesis, and thereby achieve tissue regeneration and repair. Imagine that when a part of the body is injured, the growth factors in PRP will quickly "rush to the battlefield" and direct cells to carry out repair work, allowing the wound to heal faster.
But why is the therapeutic effect of some PRP treatments not optimal?
The primary reason lies in the lack of strict quality control during the preparation process. While PRP preparation may seem simple, it actually has extremely high requirements for each step. Starting from blood collection, if the blood collection equipment is not calibrated or the collected volume is inaccurate, it may affect the subsequent platelet concentration. In the centrifugation step, different centrifugation conditions—such as time and speed—directly determine the concentration and activity of platelets and growth factors in PRP. If the centrifugation time is too short or the speed is insufficient, platelets cannot be fully concentrated, resulting in an insufficient content of growth factors. In such cases, the treatment is like "having insufficient troops," making it difficult to achieve the desired repair effect. Conversely, excessive centrifugation may damage the structure of platelets and growth factors, rendering them inactive and turning them into useless "empty shells."
Taking the treatment of diabetic foot as an example, when some irregularly prepared PRP is used on patients, the wound does not heal gradually as expected. This may be because the platelet concentration in such PRP is low and the release of growth factors is insufficient, which fails to effectively stimulate the regeneration of damaged tissue cells in the foot. The originally expected "repair army" thus becomes a "disorganized group of soldiers" that cannot form an effective therapeutic force. As a result, patients suffer unnecessary pain and the optimal treatment timing is also delayed.
Standardized personnel operation is also a crucial factor affecting PRP quality. If operators lack professional training and are not familiar with processes such as blood collection, preparation, and injection, they are likely to introduce errors in various links. For instance, failing to strictly follow the aseptic operation principles during blood collection may lead to blood contamination. When such prepared PRP is used on patients, it not only fails to treat the disease but may also cause serious complications such as infections. In the injection process, if PRP cannot be accurately injected into the treatment site, it is like shooting an arrow off-target—growth factors will be unable to act on the tissues in need of repair, and the therapeutic effect will naturally be greatly reduced.
In addition, environmental factors during the PRP preparation process cannot be ignored. The preparation must be carried out in a specific environment that meets hygiene standards to avoid microbial contamination and interference from other external factors. If the environment fails to meet the standards—such as excessive microbial content in the air—it may contaminate PRP during preparation, affecting its quality and safety.
Not all PRP products are created equal— the core lies in the difference between "quality" and "standards". Only PRP that undergoes strict quality control and is prepared in a standardized manner can exert its due powerful effect in disease treatment. Both patients and medical practitioners should fully recognize the importance of quality control, choose PRP treatments that meet standards, and jointly promote the healthy development of this advanced therapeutic technology to bring hope of recovery to more patients.
The Shuangwei Biotechnology PRP kit has the following advantages:

- High degree of automation: The preparation and extraction process is fully automated. It is composed of a disposable platelet-rich plasma preparation kit and a medical centrifuge, achieving "one-time centrifugation, one-stop sealing, and one-click preparation", reducing manual operation errors and improving the preparation efficiency and accuracy.
- Completely closed and pollution-free: The separation and extraction process is completely closed, effectively avoiding external pollution, reducing the risk of infection, and ensuring the quality, safety and reliability of the prepared PRP.
- Convenient operation: The PRP with the required concentration can be obtained only through one-time centrifugation. The whole preparation process only takes 15 minutes, which greatly shortens the preparation time and improves the clinical work efficiency.
- Precise and adjustable concentration: Through mode selection, the concentration can be precisely adjusted from 2 to 8 times. It can provide personalized PRP concentrations according to the conditions and treatment needs of different patients to achieve the best treatment effect.
- Adjustable components: Consumables can be optionally configured to prepare leukocyte PRP or complex leukocyte PRP, realizing the adjustability of PRP components and further meeting the needs of different clinical application scenarios.
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