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The development and current status of PRP in the treatment of chronic wounds
25 Mar,2025

"Body remodeling" sounds like a plot from a science fiction movie, but it is not a myth. It is a real autologous platelet-rich plasma (PRP) technology that exists in the medical field. PRP technology uses "autologous blood" as raw material to activate the body's self-healing potential, bringing new life to countless patients with chronic wounds.
As the population ages, problems such as diabetes, vascular diseases, and long-term bed rest become increasingly common, and the incidence of chronic, refractory wounds is rising year by year. Data show that there are more than 150 million osteoarthritis patients in my country, and about 2 million new cases of diabetic foot ulcers are reported each year. If these wounds are not treated in time, they may lead to infection, amputation, or even life-threatening conditions. Traditional methods such as debridement, antibiotics, and skin grafting often face problems such as long healing period, high recurrence rate, and high cost. Especially for elderly patients, the decline of body functions has greatly reduced the repair ability, and more efficient and safe solutions are urgently needed.
What is PRP? Firstly, the main components of our blood are plasma, platelets, red blood cells and white blood cells. The main components of PRP are platelets and plasma among them. Everyone knows that platelets have the function of blood coagulation, but in fact, platelets are also rich in a large number of growth factors. It is these activated growth factors that play a very important role in the regeneration and repair of our tissues. And PRP treatment is carried out by drawing one's own blood, using professional equipment and consumables to extract the platelet-rich plasma from one's own blood through centrifugation, and then treating the affected area by injection. Therefore, compared with traditional drug treatment, PRP is derived from autologous blood, there is no risk of immune rejection or disease transmission, and it has good safety. After more than 40 years of research and development, the technology of PRP has been fully studied both at home and abroad. There have been a large number of clinical studies and applications, benefiting countless patients.
There was a 68-year-old female patient with a 10-year history of diabetes who had been bedridden for a long time. Due to a stage IV pressure ulcer on the sacrococcygeal region, with an area of 5 cm × 4 cm, reaching as deep as the fascia, accompanied by yellow necrotic tissue, exudate, and an unpleasant odor, multiple debridements and applications of silver ion dressings had been ineffective. Her wound was difficult to heal due to the microcirculatory disorder caused by diabetes, and her family members refused a skin grafting operation. Later, upon the doctor's recommendation, she was treated with PRP. In the first week, thorough debridement was carried out, and the infection was controlled (antibiotics were used according to the results of the drug sensitivity test), and the wound surface was covered with PRP gel and sealed with a hydrocolloid dressing. From the second to the fourth week, PRP injections were given once a week (multiple-point injections at the wound base and edges), and negative pressure wound therapy (NPWT) was combined to promote granulation growth. From the fifth to the eighth week, PRP was sprayed once every two weeks, and a silicone foam dressing was used instead. In the fourth week, the necrotic tissue of this patient was completely removed, and the coverage rate of red granulation tissue was more than 90%. After a 6-month follow-up, there was no recurrence. The effect was very remarkable, and the patient also expressed great satisfaction.
Although PRP is an excellent treatment method, the equipment and consumables required for preparing PRP must also meet national standards. Currently, there is a wide variety of consumables on the market. Shuangwei Biotechnology, having been deeply engaged in the field of blood safety for nearly 30 years, is a leading player in the field of blood transfusion technology in China. It has accumulated rich experience in blood safety management. In order to meet the clinical needs, it has nurtured and incubated a brand-new Class III medical device product, the "Disposable Platelet-Rich Plasma Preparation Kit", which obtained a new certificate in September last year.
The fully automatic PRP preparation system of Shuangwei Biotechnology is composed of a disposable platelet-rich plasma preparation kit and a medical centrifuge. It is mainly composed of a PRP consumable preparation device, a syringe, a suction assembly, a venous blood sample collection needle and an injection needle. The suction assembly is composed of a syringe and a suction part. The suction part includes a fixing plate, a pressure ring, a suction needle and a multi-functional suction tube.
The consumables of Shuangwei Biotechnology can be used in combination with the dedicated centrifuges independently developed and produced by Shuangwei Biotechnology, achieving: one-time centrifugation, one-stop sealing, and one-click preparation.
The preparation and suction processes are fully automatic, with the concentration accurately adjustable within a range of 2 to 8 times. The separation and extraction processes are fully enclosed and free from pollution. The entire preparation process only takes 20 minutes, realizing the "one-time centrifugation, one-stop sealing, and one-click preparation" of PRP components. It can perform separation, positioning, puncturing, adjusting the separation interface, precisely controlling the extraction speed and the extraction volume, thus overcoming the limitations of human operation.
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